Antonio Heras-Garvin Selected Research

Synucleins

11/2021	ATH434 Reduces α-Synuclein-Related Neurodegeneration in a Murine Model of Multiple System Atrophy.
1/2021	The Concept of α-Synuclein Strains and How Different Conformations May Explain Distinct Neurodegenerative Disorders.
1/2021	Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease.
1/2020	High-salt diet does not boost neuroinflammation and neurodegeneration in a model of α-synucleinopathy.
1/2020	Targeting α-synuclein by PD03 AFFITOPE® and Anle138b rescues neurodegenerative pathology in a model of multiple system atrophy: clinical relevance.
11/2019	The molecular tweezer CLR01 reduces aggregated, pathologic, and seeding-competent α-synuclein in experimental multiple system atrophy.
1/2019	Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy.

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Antonio Heras-Garvin Research Topics

Disease

9	Multiple System Atrophy 11/2021 - 03/2016
4	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2021 - 01/2020
4	Synucleinopathies 11/2021 - 01/2020
4	Parkinson Disease (Parkinson's Disease) 01/2021 - 01/2020
2	Dementia (Dementias) 01/2021 - 01/2020
1	Olivopontocerebellar Atrophies (Olivopontocerebellar Atrophy) 11/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021
1	Neuroinflammatory Diseases 01/2020
1	Multiple Sclerosis 01/2020
1	Inflammation (Inflammations) 01/2020
1	Gliosis 01/2020
1	Proteostasis Deficiencies 01/2019

Drug/Important Bio-Agent (IBA)

7	SynucleinsIBA 11/2021 - 01/2019
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2020
2	3- (1,3- benzodioxol- 5- yl)- 5- (3- bromophenyl)- 1H- pyrazoleIBA 01/2020 - 01/2019
1	ATH434IBA 11/2021
1	Amyloid (Amyloid Fibrils)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	ChemokinesIBA 01/2020
1	SaltsIBA 01/2020
1	CytokinesIBA 01/2020
1	PrionsIBA 03/2016

Therapy/Procedure

1	Therapeutics 01/2020